Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669917 | 0.86 | GCGR (0.43) | GCG | |
| SCHEMBL2669883 | 0.86 | GCG (0.44) | GCGNAMPTALDH1A1ADRB2HDAC6 | |
| SCHEMBL9070785 | 0.85 | GCG (0.43) | GCGNAMPTHDAC6PARP1MCHR1 | |
| SCHEMBL13069678 | 0.75 | NAMPT (0.34) | NAMPTALDH1A1CNR1CNR2 | |
| SCHEMBL2669921 | 0.72 | GCG (0.41) | GCGNAMPTHDAC6MCHR1 | |
| SCHEMBL2669985 | 0.72 | GCGR (0.47) | GCG | |
| SCHEMBL13069224 | 0.71 | GCG (0.44) | GCG | |
| SCHEMBL2669983 | 0.71 | GCG (0.41) | GCGNAMPTHDAC6MCHR1 | |
| SCHEMBL2669960 | 0.67 | GCG (0.40) | GCGNAMPTALDH1A1ADRB2MCHR1 | |
| SCHEMBL13271307 | 0.66 | NAMPT (0.36) | GCGNAMPTALDH1A1ADRB2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |