⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16474376 | 0.76 | HTT (0.33) | — | |
| SCHEMBL16474372 | 0.71 | — | — | |
| SCHEMBL11978470 | 0.65 | PAK4 (0.35) | — | |
| SCHEMBL11957357 | 0.63 | ADORA2A (0.33) | — | |
| SCHEMBL24423245 | 0.62 | ACHE (0.37) | — | |
| SCHEMBL19321627 | 0.61 | LMNA (0.38) | — | |
| SCHEMBL12316241 | 0.61 | BRD4 (0.42) | — | |
| SCHEMBL13487532 | 0.61 | — | — | |
| SCHEMBL22057943 | 0.59 | HTT (0.36) | — | |
| SCHEMBL23400503 | 0.59 | HTT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |