Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786681 | 0.97 | L3MBTL1 (0.57) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL26706114 | 0.90 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL26705884 | 0.89 | FADS1 (0.58) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL17208120 | 0.86 | FADS1 (0.58) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL15786680 | 0.86 | L3MBTL1 (0.54) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL22446047 | 0.78 | TP53 (0.52) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL19973484 | 0.77 | TP53 (0.46) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL19973483 | 0.77 | TP53 (0.46) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21189386 | 0.77 | TP53 (0.46) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL19973509 | 0.76 | TP53 (0.47) | NPC1RAB9ASMN1; SMN2TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601216-B1 | SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-25 | — | — | EP | disclosed |