Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26672982 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL22666718 | 0.94 | TSHR (0.42) | SMN1; SMN2CYP2D6PTGS2PTGS1TSHR | |
| SCHEMBL26673690 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL25613528 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL26705907 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL25613491 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL25613451 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL26672978 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL25613447 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL22666659 | 0.79 | TSHR (0.58) | ALDH1A1LMNASMN1; SMN2CYP2D6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159716-A1 | POLYPHENYLENES, METHODS, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159716-A1 | POLYPHENYLENES, METHODS, AND USES THEREOF | PICALM, PARN, PHOSPHO1 | ALDH1A1 4799/4885KDM4E 4687/4885MAPT 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.