SCHEMBL267071

SCHEMBL267071

FC(F)(F)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
IDO1 P14902 1/20 0.48
AGXT P21549 1/20 0.46
PTPN1 P18031 1/20 0.45
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 3/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A3 Q01959 2/20 0.40
CES1 P23141 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL27525496 0.84 PTPN1 (0.43) TSHRPTPN1KDM4EPOLBALDH1A1
SCHEMBL16559626 0.83 IDO1 (0.47) IDO1AGXTALDH1A1MAOB
SCHEMBL3434137 0.81 TSHR (0.48) TSHRIDO1AGXTPTPN1ALDH1A1
SCHEMBL22346842 0.81 TSHR (0.54) TSHRIDO1AGXTPTPN1KDM4E
SCHEMBL11192334 0.79 TSHR (0.46) TSHRIDO1AGXTPTPN1KDM4E
SCHEMBL23227683 0.79 TSHR (0.52) TSHRIDO1AGXTPTPN1KDM4E
SCHEMBL11526962 0.79 ALDH1A1 (0.53) ALDH1A1SLC6A2SLC6A3LMNACYP2C19
SCHEMBL10591074 0.78 IDO1 (0.50) IDO1KDM4EALDH1A1CA2SLC6A2
SCHEMBL7590606 0.78 IDO1 (0.54) IDO1AGXTCA1CA2CA9
SCHEMBL10523360 0.78 TSHR (0.44) TSHRIDO1AGXTPTPN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012034-A Cooling liquid, liquid cooling module and electronic equipment 华为技术有限公司 2026-05-12 CN claimed
CN-119638588-A Trifluoromethyl benzyl ether substituted amino acid derivative, preparation method and application thereof 中国医学科学院药物研究所 2025-03-18 CN claimed
CN-118994765-A Insulation and pressure-resistant material for cable 安徽朗达电线电缆有限公司 2024-11-22 CN claimed
CN-117895064-B Phosphate polymer quasi-solid electrolyte, in-situ solid immobilization preparation method and application 深圳大学 2024-11-19 CN claimed
CN-118325411-B Antifouling paint composition and preparation method thereof 广州翔铭环保新材料有限公司 2024-08-09 CN claimed
CN-118325411-A Antifouling paint composition and preparation method thereof 广州翔铭环保新材料有限公司 2024-07-12 CN claimed
CN-117895064-A Phosphate polymer quasi-solid electrolyte, in-situ solid immobilization preparation method and application 深圳大学 2024-04-16 CN claimed
CN-115784839-A Preparation method of 4-cyclohexyl-3- (trifluoromethyl) benzyl alcohol 浙江工业大学 2023-03-14 CN claimed
CN-113999342-B Migratable polymer-based functional modifier and preparation method and application thereof 厦门大学 2022-08-12 CN claimed
US-20220033634-A1 CURABLE FLUORINE-BASED ELASTOMER COMPOSITE AND CURED PRODUCT THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2022-02-03 US claimed
WO-2007139933-A2 PROCESSES FOR THE PREPARATION OF R-(+)-3-(CARBAMOYL METHYL)-5-METHYLHEXANOIC ACID AND SALTS THEREOF TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-12-06 WO claimed
US-6979690-B2 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators PFIZER INC. (US) 2005-12-27 US claimed
CN-1226258-C Process for producing fluorinated methyl-benzyl alcohol SHOWAN DENKO K K (JP) 2005-11-09 CN claimed
EP-1017692-B1 4-HETEROARYL-TETRAHYDROQUINOLINES AND THEIR USE AS INHIBITORS OF THE CHOLESTERIN-ESTER TRANSFER PROTEIN BAYER HEALTHCARE AG (DE) 2004-03-03 EP claimed
CN-1466560-A Process for producing fluorinated methyl-benzyl alcohol �Ѻ͵繤��ʽ���� 2004-01-07 CN claimed
US-20030207875-A1 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators PFIZER INC 2003-11-06 US claimed
WO-2003057688-A2 OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS PFIZER JAPAN INC. (JP) 2003-07-17 WO claimed
EP-1325921-A2 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators Pfizer Inc. (US) 2003-07-09 EP claimed
WO-1993012080-A1 SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1993-06-24 WO claimed
EP-0271780-A2 Substituted 1-benzylsulfonyl-3-heteroaryl(thio) urea BAYER AG (DE) 1988-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207875-A1 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators HRH4, HRH2, HTR4 TSHR 148/4885IDO1 560/4885AGXT 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.