Biguanide

Biguanide

SCHEMBL2670745

N=C(N)NC(=N)N.O=[N+]([O-])O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Biguanide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.47
CA5B Q9Y2D0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL332554 0.87 CA5A (0.40) CA5ACA5B
Nitric Acid SCHEMBL28993751 0.87 CA5A (0.40) CA5ACA5B
Pimagedine SCHEMBL4539956 0.82 CA5A (0.47) CA5ACA5B
Pimagedine SCHEMBL239259 0.82
Nitric Acid SCHEMBL19458370 0.82 CA5A (0.47) CA5ACA5B
Pimagedine SCHEMBL27817337 0.82 CA5A (0.47) CA5ACA5B
Guanidine SCHEMBL11252247 0.81 CA5A (0.61) CA5ACA5B
Guanidine SCHEMBL17844261 0.81 CA5A (0.61) CA5ACA5B
Guanidine SCHEMBL1013287 0.81 CA5A (0.61) CA5ACA5B
Guanidine SCHEMBL742686 0.81 CA5A (0.61) CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119356009-B Use of biguanides or biguanides nitrate as nonlinear optical crystals 江西师范大学 2025-03-25 CN claimed
CN-119356009-A Use of biguanides or biguanides nitrate as nonlinear optical crystals 江西师范大学 2025-01-24 CN claimed
CN-119280450-A Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof 孙国明 2025-01-10 CN claimed
CN-118844836-A Long-acting disinfection and sterilization wet (towel) paper 孙国明 2024-10-29 CN claimed
CN-118844448-A Preparation method of long-acting antibacterial liquid 孙国明 2024-10-29 CN claimed
CN-108641077-B Synthetic method of polyphenyl ether 广东省石油与精细化工研究院 2020-07-28 CN claimed
CN-110804198-A Preparation method of antibacterial cellulose degradable composite membrane 石家庄学院 2020-02-18 CN claimed
CN-110804179-A High-molecular ionic liquid with good film forming property and long-term antibacterial activity and application thereof 石家庄学院 2020-02-18 CN claimed
CN-106380598-B A kind of synthetic method of degradation property and its application 石家庄学院 2018-10-19 CN claimed
CN-108641077-A A kind of synthetic method of polyphenylene oxide 广东省石油与精细化工研究院 2018-10-12 CN claimed
CN-107541006-A Antibacterial polyacrylonitrile-butadiene-styrene plastic and preparation method thereof 芜湖蓝天工程塑胶有限公司 2018-01-05 CN claimed
CN-107541054-A Antibacterial nylon and preparation method thereof 芜湖蓝天工程塑胶有限公司 2018-01-05 CN claimed
CN-107541060-A Antibacterial agent and preparation method and application thereof 芜湖蓝天工程塑胶有限公司 2018-01-05 CN claimed
CN-107501726-A Antibacterial polypropylene plastic and preparation method thereof 芜湖蓝天工程塑胶有限公司 2017-12-22 CN claimed
CN-107501876-A Antibacterial polyethylene glycol terephthalate plastic and preparation method thereof 芜湖蓝天工程塑胶有限公司 2017-12-22 CN claimed
CN-106380598-A Synthesis method and application of high-polymer ionic liquid 石家庄学院 2017-02-08 CN claimed
CN-119356009-B Use of biguanides or biguanides nitrate as nonlinear optical crystals 江西师范大学 2025-03-25 CN disclosed
CN-119356009-B Use of biguanides or biguanides nitrate as nonlinear optical crystals 江西师范大学 2025-03-25 CN disclosed
US-20040134576-A1 Copper containing igniter composition for a gas generant AUTOLIV ASP, INC. 2004-07-15 US disclosed
WO-1992008464-A1 SUBSTITUTED UREA AND RELATED CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-05-29 WO disclosed