Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408386 | 0.83 | OPRM1 (0.43) | KDM4CCDC7CDK2OPRM1OPRD1 | |
| SCHEMBL24110147 | 0.79 | CDC7 (0.35) | KDM4CCDC7CDK2DRD2SLC6A4 | |
| SCHEMBL7569682 | 0.78 | HRH3 (0.40) | KDM4CCDC7CDK2OPRM1OPRD1 | |
| SCHEMBL29856216 | 0.75 | GSK3B (0.53) | AOC3KDM4CCDC7CDK2KCNH2 | |
| SCHEMBL24110143 | 0.75 | SCN9A (0.35) | CDC7CDK2MKNK2TGFBR1RAPGEF4 | |
| SCHEMBL7497513 | 0.74 | OPRM1 (0.34) | KDM4COPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL24110591 | 0.73 | CDC7 (0.35) | CDC7CDK2MKNK2TGFBR1RAPGEF4 | |
| SCHEMBL29423860 | 0.72 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL6646174 | 0.72 | CDC7 (0.45) | CDC7CDK2MKNK2TGFBR1RAPGEF4 | |
| SCHEMBL367111 | 0.72 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265613-A1 | BENZENE RING COMPOUND AND USE THEREOF | Nanjing Shijiang Medicine Technology Co., Ltd (CN) | 2023-10-25 | — | — | EP | disclosed |