SCHEMBL26711237

SCHEMBL26711237

C=CCCC(C)(C)C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 4/20 0.35
LMNA P02545 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
HSD17B10 Q99714 1/20 0.31
USP2 O75604 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048461 0.81 SMN1; SMN2 (0.35) L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2
SCHEMBL10684759 0.79 MGAM (0.41) L3MBTL1ALDH1A1LMNATSHRCYP4F2
SCHEMBL5527027 0.77 CYP4F2 (0.52) L3MBTL1ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL5526187 0.77 CYP4F2 (0.52) L3MBTL1ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL7668553 0.77 ALDH1A1 (0.37) L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2
SCHEMBL5523761 0.77 CYP4F2 (0.52) L3MBTL1ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL5517737 0.77 CYP4F2 (0.52) L3MBTL1ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL7213719 0.74 ALDH1A1 (0.42) ALDH1A1LMNACYP4F2CYP4A11HSD17B10
SCHEMBL11104754 0.74 CYP4F2 (0.58) L3MBTL1ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL3251799 0.74 CYP4F2 (0.53) L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346702-A1 LIPID NANOPARTICLES METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed
US-20230348361-A1 IONIZABLE LIPID COMPOUNDS METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348361-A1 IONIZABLE LIPID COMPOUNDS PHOSPHO1, SLC10A1, SLCO4C1 L3MBTL1 1883/4885MAPK1 3609/4885ALDH1A1 2174/4885
US-20230346702-A1 LIPID NANOPARTICLES ABCB4, NPC1L1, CHMP4B L3MBTL1 3288/4885MAPK1 2968/4885ALDH1A1 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.