Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 9/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559838 | 0.88 | POLB (0.44) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL24440871 | 0.87 | POLB (0.43) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL15338931 | 0.86 | POLB (0.51) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL19803990 | 0.86 | TDP1 (0.43) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL16559829 | 0.85 | POLB (0.47) | HTTPOLBAPEX1TDP1KMT2A | |
| SCHEMBL18494395 | 0.84 | HTT (0.41) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL22845690 | 0.84 | POLB (0.41) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL25936691 | 0.84 | HTT (0.41) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL24440804 | 0.84 | POLB (0.41) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL22459820 | 0.84 | POLB (0.42) | HTTPOLBAPEX1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023209049-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023203043-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-26 | — | — | WO | disclosed |