Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 10/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524313 | 0.81 | CSNK1D (0.48) | CSNK1DMAPK14THRBTGFBR1CSNK1E | |
| SCHEMBL24348532 | 0.80 | TGFBR1 (0.56) | CSNK1DMAPK14THRBTGFBR1CSNK1A1 | |
| SCHEMBL30403321 | 0.80 | CSNK1D (0.63) | CSNK1DMAPK14THRBTGFBR1CSNK1A1 | |
| SCHEMBL26720854 | 0.80 | CSNK1D (0.63) | CSNK1DMAPK14THRBTGFBR1CSNK1A1 | |
| SCHEMBL26720251 | 0.79 | CSNK1D (0.54) | CSNK1DMAPK14THRBTGFBR1CSNK1A1 | |
| SCHEMBL26720525 | 0.78 | CSNK1D (0.44) | CSNK1DMAPK14THRBTGFBR1SIGMAR1 | |
| SCHEMBL26720311 | 0.77 | SIGMAR1 (0.39) | CSNK1DMAPK14THRBTGFBR1SIGMAR1 | |
| SCHEMBL29514461 | 0.77 | SIGMAR1 (0.39) | CSNK1DMAPK14THRBTGFBR1SIGMAR1 | |
| SCHEMBL26720313 | 0.77 | SIGMAR1 (0.39) | CSNK1DMAPK14THRBTGFBR1SIGMAR1 | |
| SCHEMBL26720315 | 0.77 | SIGMAR1 (0.39) | CSNK1DMAPK14THRBTGFBR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK1G1 | CSNK1D 1/4885MAPK14 453/4885THRB 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.