⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645584 | 0.80 | DGAT1 (0.34) | — | |
| SCHEMBL30134974 | 0.80 | DGAT1 (0.34) | — | |
| SCHEMBL29514366 | 0.79 | UCHL1 (0.33) | — | |
| SCHEMBL25983802 | 0.79 | UCHL1 (0.33) | — | |
| SCHEMBL26720534 | 0.78 | DGAT1 (0.32) | — | |
| SCHEMBL26720538 | 0.78 | KMT2A (0.34) | — | |
| SCHEMBL18975908 | 0.76 | DGAT1 (0.31) | — | |
| SCHEMBL21858190 | 0.75 | — | — | |
| SCHEMBL26720123 | 0.75 | NOTUM (0.32) | — | |
| SCHEMBL24566554 | 0.74 | GSK3A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |