SCHEMBL26720591

SCHEMBL26720591

CC1(C)OB(c2c(F)cnc3c2cnn3COCC[Si](C)(C)C)OC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.33
DGAT1 O75907 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26720595 0.83 DGAT1 (0.30) DGAT1
SCHEMBL29514366 0.79 UCHL1 (0.33)
SCHEMBL25983802 0.79 UCHL1 (0.33)
SCHEMBL26603766 0.78 F2RL1 (0.35) F2RL1DGAT1
SCHEMBL29514264 0.78 F2RL1 (0.35) F2RL1DGAT1
SCHEMBL25368395 0.76 DGAT1 (0.33) DGAT1
SCHEMBL29493773 0.76 DGAT1 (0.33) DGAT1
SCHEMBL29705322 0.76 FFAR1 (0.33) DGAT1
SCHEMBL27215187 0.76 FFAR1 (0.33) DGAT1
SCHEMBL16050460 0.76 UCHL1 (0.36) F2RL1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
EP-4214214-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN Pharmaceutica NV (BE) 2023-07-26 EP disclosed
WO-2022058920-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2022-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS CSNK1D, CSNK1A1, CSNK1G1 F2RL1 3897/4885DGAT1 3129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.