SCHEMBL26729276

SCHEMBL26729276

CC(C)CN1c2ccc(N(C)C)cc2Sc2cc(N(C)C)ccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 1/20 0.49
▸ MAPK1 P28482 4/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CYP2D6 P10635 5/20 0.46
▸ CHRM2 P08172 5/20 0.46
▸ HTR1A P08908 5/20 0.46
▸ CHRM1 P11229 5/20 0.46
▸ ADRA1A P35348 5/20 0.46
▸ OPRM1 P35372 5/20 0.46
▸ DRD3 P35462 5/20 0.46
▸ KCNH2 Q12809 5/20 0.46
▸ ADRA2A P08913 4/20 0.46
▸ DRD1 P21728 4/20 0.46
▸ PTGS1 P23219 4/20 0.46
▸ SLC6A2 P23975 3/20 0.46
▸ SLC6A4 P31645 3/20 0.46
▸ LMNA P02545 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19404346 0.81 SNCA (0.53) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL3419052 0.75 SNCA (0.76) SNCAMAPK1KMT2ATDP1MEN1
Bromide SCHEMBL2590643 0.75 HTR2A (0.45) MAPK1KMT2ATDP1CYP2D6CHRM2
SCHEMBL30595091 0.75 MAPK1 (0.58) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL23999391 0.74 SNCA (0.55) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL14593435 0.74 MAPK1 (0.56) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL14264321 0.73 SNCA (0.45) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL27750062 0.72 KMT2A (0.55) SNCAMAPK1KMT2ATDP1MEN1
SCHEMBL16316914 0.72 PTGS1 (0.73) MAPK1KMT2ATDP1MEN1CYP2D6
SCHEMBL3415950 0.71 SNCA (0.53) SNCAMAPK1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382938-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2023-11-30 — — US disclosed
US-20230382938-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2023-11-30 — — US disclosed
WO-2023205262-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382938-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM HCN2, HCN1, HCN3 SNCA 2121/4885MAPK1 403/4885KMT2A 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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