Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573710 | 0.87 | PTGDR2 (0.39) | PPARGPPARDPPARAP2RX3 | |
| SCHEMBL2572603 | 0.85 | PTGDR2 (0.32) | — | |
| SCHEMBL2580572 | 0.84 | TGFBR1 (0.32) | — | |
| SCHEMBL2580577 | 0.83 | TGFBR1 (0.30) | — | |
| SCHEMBL12167853 | 0.79 | PTGDR2 (0.40) | PPARGPPARDPPARA | |
| SCHEMBL3779601 | 0.77 | PPARA (0.39) | PPARGPPARDPPARAP2RX3 | |
| SCHEMBL2571385 | 0.74 | PTGDR2 (0.41) | PPARDP2RX3 | |
| SCHEMBL3780751 | 0.73 | TSHR (0.44) | PPARGPPARDPPARAP2RX3 | |
| SCHEMBL3782820 | 0.73 | P2RX3 (0.36) | PPARDPPARAP2RX3 | |
| SCHEMBL2573868 | 0.72 | PTGDR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173812-B2 | Quinolines and their therapeutic use | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2012-05-08 | — | — | US | disclosed |
| US-20100144787-A1 | Quinolines and Their Therapeutic Use | GB005, INC. | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144787-A1 | Quinolines and Their Therapeutic Use | CHRM3, CHRM2, HRH1 | PPARG 1078/4885PPARD 1386/4885PPARA 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.