Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL30887985 | 0.93 | KDM4E (0.51) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL16343556 | 0.86 | ELANE (0.50) | KDM4EHSD17B10HPGDALDH1A1RECQL | |
| SCHEMBL8645321 | 0.81 | SMN1; SMN2 (0.57) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL17647315 | 0.80 | SORT1 (0.42) | KDM4EHSD17B10HPGDALDH1A1CYP1A2 | |
| SCHEMBL2867637 | 0.79 | HTT (0.68) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL15058018 | 0.79 | HTT (0.58) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL28632141 | 0.78 | HTT (0.61) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL446113 | 0.78 | HTT (0.77) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL29682980 | 0.78 | HTT (0.77) | HTTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL9678819 | 0.77 | KDM4E (0.47) | HTTKDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173763-B1 | Carbon nanofibers and nanotubes grafted with a hyperbranched poly (ether-ketone) and its derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-05-08 | — | — | US | disclosed |
| US-7732642-B1 | Arylcarbonylated detonation nanodiamonds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2010-06-08 | — | — | US | disclosed |
| US-7005550-B1 | Arylcarbonylated vapor-grown carbon nanofibers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2006-02-28 | — | — | US | disclosed |