SCHEMBL267327

SCHEMBL267327

O=C(Cl)c1cccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.56
TSHR P16473 3/20 0.52
CTSD P07339 1/20 0.50
ALDH1A1 P00352 2/20 0.49
TDP1 Q9NUW8 3/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
DHODH Q02127 1/20 0.41
GLA P06280 1/20 0.41
KCNMA1 Q12791 1/20 0.41
APEX1 P27695 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10789939 0.88 ALDH1A1 (0.48) GPR35TSHRCTSDALDH1A1TDP1
4-Nitrobenzoyl Chloride SCHEMBL8724565 0.88 ALDH1A1 (0.63) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL7263414 0.85 GPR35 (0.60) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL3671 0.85 TSHR (0.68) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL7417028 0.85 GPR35 (0.60) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL30893562 0.85 TSHR (0.68) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL16267318 0.83 TSHR (0.66) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL1456960 0.83 GPR35 (0.67) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL3278518 0.83 ALDH1A1 (0.46) GPR35TSHRCTSDALDH1A1TDP1
SCHEMBL10824707 0.83 TSHR (0.66) GPR35TSHRCTSDALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725252-A Sulfonyl iminopolyurethane single-ion polymer electrolyte membrane, and preparation method and application thereof 哈尔滨工业大学 2024-10-01 CN claimed
CN-112778180-A Vitamin D2Preparation method of (1) 广州艾格生物科技有限公司 2021-05-11 CN claimed
CN-110379293-A Aobvious blue thermal label of a kind of bottom and preparation method thereof 广东天元实业集团股份有限公司 2019-10-25 CN claimed
CN-109917029-A A kind of measuring method of aliphatic polyether functionality polyols and distribution 内蒙合成化工研究所 2019-06-21 CN claimed
CN-109627279-A A kind of preparation method of activity of vitamin d3 intermediate 浙江花园营养科技有限公司 2019-04-16 CN claimed
CN-109633041-A The method that derivatization HPLC method measures protona in drug 广东食品药品职业学院 2019-04-16 CN claimed
CN-108929243-A A kind of diamine monomer and its preparation method and application containing asymmetric fluorophore structure 吉林大学 2018-12-04 CN claimed
CN-108918700-A Method that is a kind of while detecting statin side chain and its enantiomter impurity 合肥合源药业有限公司 2018-11-30 CN claimed
CN-105424823-B The detection method of polyamines in a kind of Tobacco Root, stem and leaf 贵州省烟草科学研究院 2018-05-25 CN claimed
CN-107974444-A The lysine decarboxylase in new Huperzia serrata source and its encoding gene and application 中国科学院上海生命科学研究院 2018-05-01 CN claimed
CN-1807398-A Diamine containing benzophenone structure and its preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-07-26 CN claimed
CN-1259305-C Fluorine-aromatic diamine with side chain having methyltrifluoride substituted benzene and diphenyl ether and preparation process and use thereof CHINESE ACAD INST CHEMISTRY (CN) 2006-06-14 CN claimed
WO-2006028745-A1 HIGH PURITY, HIGH MOLECULAR WEIGHT METHOXY-POLYETHYLENGLYCOLS (MPEG) DOW GLOBAL TECHNOLOGIES INC. (US) 2006-03-16 WO claimed
US-20060045866-A1 Novel high purity and high molecular weight mPEG alcohol compositions CHAPPELOW CHRIS 2006-03-02 US claimed
CN-1740181-A New pirkle-type chiral fixed phase and its prepn process UNIV SHENYANG PHARMACY (CN) 2006-03-01 CN claimed
CN-1742036-A Polymide resin for non-rubbing vertical alignment materials and preparation method thereof YONG-BAE KIM (KR) 2006-03-01 CN claimed
CN-1733718-A Photochemical synthesis of vitamin D2Method (2) CHINESE ACAD TECH INST PHYSICS (CN) 2006-02-15 CN claimed
US-20040158030-A1 Diamine, acid dianhydride, polymide composition having reactive group obtained therefrom, and processes for producing these KANEKA CORPORATION (JP) 2004-08-12 US claimed
CN-1501921-A Diamine, acid dianhydride, polyimide composition having reactive group and comprising the same, and method for producing the same 钟渊化学工业株式会社 2004-06-02 CN claimed
CN-1434024-A Fluorine-aromatic diamine with side chain having methyltrifluoride substituted benzene and diphenyl ether and preparation process and use thereof CHINESE ACAD INST CHEMISTRY (CN) 2003-08-06 CN claimed