Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674004 | 0.81 | POLB (0.39) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL2674009 | 0.80 | POLB (0.52) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL31343022 | 0.80 | POLB (0.48) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL8491773 | 0.80 | POLB (0.45) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL7632645 | 0.79 | POLB (0.48) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL7199260 | 0.79 | POLB (0.41) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL2056493 | 0.78 | — | — | |
| SCHEMBL887176 | 0.78 | POLB (0.42) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL28799641 | 0.77 | POLB (0.53) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL5666376 | 0.77 | POLB (0.53) | POLBLMNAPDE3ACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173377-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |