⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365610 | 0.84 | POLG (0.38) | — | |
| SCHEMBL6574062 | 0.83 | — | — | |
| SCHEMBL5396749 | 0.82 | POLB (0.31) | — | |
| SCHEMBL5488005 | 0.80 | POLB (0.39) | — | |
| SCHEMBL8517853 | 0.79 | LMNA (0.40) | — | |
| SCHEMBL15301518 | 0.79 | TYMP (0.35) | — | |
| SCHEMBL16131335 | 0.79 | TYMP (0.35) | — | |
| SCHEMBL2674007 | 0.78 | POLB (0.41) | — | |
| SCHEMBL440942 | 0.77 | POLB (0.38) | — | |
| SCHEMBL343674 | 0.77 | POLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076461-B2 | antibody microarray for detecting incomplete deprotection of synthetic test oligonucleotides; high throughput assay; solid phase synthesis | PROTEOME SCIENCES PLC (GB) | 2011-12-13 | — | — | US | disclosed |
| US-7901892-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-08 | — | — | US | disclosed |