Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809059 | 0.76 | DUT (0.33) | DUT | |
| SCHEMBL26752020 | 0.74 | DUT (0.35) | DUT | |
| SCHEMBL28960818 | 0.73 | DUT (0.34) | DUT | |
| SCHEMBL6114675 | 0.68 | DUT (0.34) | DUT | |
| SCHEMBL27032615 | 0.67 | DUT (0.46) | DUT | |
| SCHEMBL26752005 | 0.67 | DUT (0.34) | DUT | |
| SCHEMBL14745028 | 0.66 | MCL1 (0.40) | DUT | |
| SCHEMBL13560548 | 0.65 | DGAT1 (0.32) | DUT | |
| SCHEMBL14788253 | 0.65 | DUT (0.35) | DUT | |
| SCHEMBL30271106 | 0.65 | TAAR1 (0.43) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308570-A1 | MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2024-01-24 | — | — | EP | disclosed |
| CN-117425661-A | Macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2024-01-19 | — | — | CN | disclosed |
| CN-115996932-A | New macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2023-04-21 | — | — | CN | disclosed |
| EP-4146658-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2023-03-15 | — | — | EP | disclosed |
| WO-2022194976-A1 | MACROCYCLIC LRRK2 KINASE INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2022-09-22 | — | — | WO | disclosed |