SCHEMBL2676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1984	0.90	LPAR1 (0.42)	FFAR4TSHRFLT1KDRLPAR1
	SCHEMBL1752	0.87	KCNA3 (0.46)	KMT2AMEN1NPSR1LMNATSHR
	SCHEMBL1879	0.84	KMT2A (0.40)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL1859	0.83	KCNA3 (0.37)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL14214	0.83	LPAR1 (0.43)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL2636106	0.83	LPAR1 (0.47)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL2761456	0.83	KMT2A (0.36)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL1083	0.82	KCNA3 (0.49)	TSHRALDH1A1OPRM1OPRD1OPRK1
	SCHEMBL2231	0.80	MEN1 (0.40)	KMT2AMEN1TDP1NPSR1LMNA
	SCHEMBL2232	0.80	LMNA (0.39)	KMT2AMEN1TDP1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.