Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032303 | 0.83 | NPC1 (0.47) | MAPTMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL2122144 | 0.76 | MAPT (0.49) | MAPTL3MBTL1MEN1KMT2AHTT | |
| SCHEMBL102602 | 0.76 | MAPT (0.77) | EGFRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL5154337 | 0.73 | KMT2A (0.41) | MAPTL3MBTL1MEN1KMT2ARECQL | |
| SCHEMBL4598888 | 0.72 | POLB (0.39) | MAPTL3MBTL1KMT2AHTTPOLB | |
| SCHEMBL2675694 | 0.72 | MAPT (0.54) | EGFRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL14655347 | 0.71 | POLB (0.41) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL7099122 | 0.71 | EGFR (0.55) | EGFRMAPTMEN1KMT2AHTT | |
| SCHEMBL1843804 | 0.71 | MEN1 (0.48) | EGFRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7164868 | 0.70 | MAPT (0.84) | MAPTL3MBTL1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073945-B2 | Alpha-IIb-beta-3 inhibitors and uses thereof | THE ROCKEFELLER UNIVERSITY (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120190645-A1 | Organic compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
| US-8173661-B2 | Alpha-IIB-beta-3 inhibitors and uses thereof | THE ROCKEFELLER UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100150913-A1 | ORGANIC COMPOUNDS | THE ROCKEFELLER UNIVERSITY (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2008057601-A2 | ORGANIC COMPOUNDS | THE ROCKEFELLER UNIVERSITY (US) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190645-A1 | Organic compounds | ICAM1, VCAM1, PLAT | EGFR 2610/4885MAPT 2102/4885L3MBTL1 1534/4885 |
| US-20100150913-A1 | ORGANIC COMPOUNDS | ICAM1, VCAM1, PLAT | EGFR 2610/4885MAPT 2102/4885L3MBTL1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.