Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205052 | 0.79 | TDP1 (0.42) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL5585097 | 0.77 | TDP1 (0.41) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL456245 | 0.77 | TDP1 (0.44) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL6978074 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1TDP1RAB9A | |
| SCHEMBL1173928 | 0.75 | TDP1 (0.41) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL831218 | 0.73 | TDP1 (0.37) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL5506758 | 0.73 | AR (0.48) | KMT2AMEN1RAB9ANPC1RECQL | |
| SCHEMBL2676405 | 0.73 | EGFR (0.48) | KMT2AMEN1ALDH1A1TDP1RAB9A | |
| SCHEMBL40607 | 0.73 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1TDP1SIGMAR1 | |
| SCHEMBL16519973 | 0.73 | TDP1 (0.48) | KMT2AMEN1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740947-A2 | FLUORESCENT DYES AND COMPLEXES | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005098437-A2 | FLUORESCENT DYES AND COMPLEXES | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD (GB) | 2005-10-20 | — | — | WO | disclosed |
| US-5622970-A | CONTROLLING GRAFT REJECTION | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1997-04-22 | — | — | US | disclosed |
| US-5516797-A | SUPPRESSING GRAFT REJECTION | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1996-05-14 | — | — | US | disclosed |
| US-5330993-A | Immunosuppressive compounds | VERTEX PHARMACEUTICALS, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5192773-A | Isomerase inhibitor | VERTEX PHARMACEUTICALS, INC. (US) | 1993-03-09 | — | — | US | disclosed |