Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | ESRRA | P11474 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16544028 | 0.86 | ESRRA (0.56) | ELANEATMKMT2ANR1H4ESRRA | |
| SCHEMBL14453833 | 0.85 | NR1H4 (0.50) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL11807412 | 0.84 | ALDH1A1 (0.46) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL17625774 | 0.83 | BACE1 (0.46) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL14453802 | 0.83 | NR1H4 (0.46) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL14173139 | 0.83 | ATM (0.43) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL7570534 | 0.81 | KDM4E (0.53) | ATMKMT2ANR1H4ESRRAGAA | |
| SCHEMBL14944766 | 0.81 | ELANE (0.53) | ELANEATMTDP1KMT2AGAA | |
| SCHEMBL13463371 | 0.80 | NR1H4 (0.43) | ELANEATMTDP1KMT2ANR1H4 | |
| SCHEMBL3193007 | 0.80 | CA2 (0.52) | ELANEATMTDP1KMT2AESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208801-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-11-02 | — | — | WO | disclosed |