Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011155 | 0.92 | CYP2C9 (0.51) | CYP2C9CYP2C19HTR2BMAPK14KEAP1 | |
| SCHEMBL24011095 | 0.92 | NAMPT (0.51) | CYP2C9CYP2C19HTR2BMAPK14KEAP1 | |
| SCHEMBL24011100 | 0.91 | CYP2C9 (0.49) | CYP2C9CYP2C19HTR2BMAPK14KEAP1 | |
| SCHEMBL24011099 | 0.91 | CYP2C9 (0.49) | CYP2C9CYP2C19HTR2BMAPK14KEAP1 | |
| SCHEMBL26765090 | 0.90 | NAMPT (0.50) | CYP2C9CYP2C19HTR2BMAPK14KEAP1 | |
| SCHEMBL24011347 | 0.84 | CYP2C9 (0.51) | CYP2C9CYP2C19HTR2BMAPK14NAMPT | |
| SCHEMBL24011315 | 0.84 | NAMPT (0.47) | CYP2C9CYP2C19HTR2BMAPK14NAMPT | |
| SCHEMBL24011238 | 0.84 | ALDH1A1 (0.57) | CYP2C9CYP2C19HTR2BMAPK14NAMPT | |
| SCHEMBL24011317 | 0.81 | CCR5 (0.54) | KEAP1NFE2L2NAMPTCHRM2MEN1 | |
| SCHEMBL24011185 | 0.80 | NAMPT (0.61) | CYP2C9HTR2BKEAP1NFE2L2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | CYP2C9 1551/4885CYP2C19 1361/4885HTR2B 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.