Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594875 | 0.82 | MEN1 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1594878 | 0.82 | MEN1 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5506993 | 0.75 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3457874 | 0.69 | — | — | |
| Water SCHEMBL10936092 | 0.67 | TSHR (0.48) | — | |
| SCHEMBL10441400 | 0.67 | LMNA (0.44) | — | |
| SCHEMBL2978617 | 0.65 | FNTA (0.34) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7353177 | 0.63 | AKR1B1 (0.56) | — | |
| SCHEMBL6026399 | 0.62 | FFAR3 (0.47) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL367757 | 0.62 | GRM8 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173813-B2 | selectively inhibit neuronal nitric oxide synthase in combination with other pharmaceutically active agents; antidepressants | NEURAXON, INC. (CA) | 2012-05-08 | — | — | US | disclosed |