SCHEMBL26772404

SCHEMBL26772404

C1=CCCC(c2nc(-c3cccc(-c4ccccc4)c3)nc(-c3ccc4c5ccccc5c5ccccc5c4c3)n2)=C1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GP6 Q9HCN6 1/20 0.32
KMO O15229 1/20 0.32
DHFR P00374 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
ATM Q13315 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22384599 0.97 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL23729317 0.97 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25621745 0.91 ESR1 (0.34) GP6KMODHFRMEN1KMT2A
SCHEMBL26773186 0.91
SCHEMBL22664865 0.89 MEN1 (0.38) KMODHFRMEN1KMT2AALDH1A1
SCHEMBL23986162 0.89 MEN1 (0.38) KMODHFRMEN1KMT2AALDH1A1
SCHEMBL20628736 0.89
SCHEMBL19791233 0.88 L3MBTL1 (0.37) GP6KMOMEN1KMT2AALDH1A1
SCHEMBL21756083 0.87 PLA2G2A (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19622641 0.86 MEN1 (0.33) DHFRMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4273126-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4273125-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed