Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099266 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL26779098 | 0.78 | MEN1 (0.35) | LMNATSHRKMT2AMEN1GABRP | |
| SCHEMBL9835163 | 0.75 | TDP1 (0.36) | LMNATSHRKMT2AMEN1TDP1 | |
| SCHEMBL226149 | 0.72 | — | — | |
| SCHEMBL23544769 | 0.71 | EPHX2 (0.36) | KMT2AMEN1GABRPGABRDGABRA1 | |
| SCHEMBL20427851 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8881391 | 0.70 | TSHR (0.43) | ALDH1A1LMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL20187495 | 0.70 | HSD17B10 (0.39) | ALDH1A1KMT2AMEN1POLBKDM4E | |
| SCHEMBL19318549 | 0.70 | TSHR (0.39) | ALDH1A1LMNASMN1; SMN2TSHRKMT2A | |
| SCHEMBL17666082 | 0.69 | ALDH1A1 (0.31) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |