Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26773180 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL26779100 | 0.76 | CA12 (0.42) | KMT2AKDM4ELMNAALOX15 | |
| SCHEMBL9835163 | 0.75 | TDP1 (0.36) | MEN1KMT2ATDP1EYA2APP | |
| SCHEMBL23544769 | 0.71 | EPHX2 (0.36) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL20427851 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2AEPHX2LMNAALOX15 | |
| SCHEMBL26773179 | 0.70 | MVD (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL20187495 | 0.70 | HSD17B10 (0.39) | MEN1KMT2AKDM4E | |
| SCHEMBL19318549 | 0.70 | TSHR (0.39) | MEN1KMT2ATDP1EYA2APP | |
| SCHEMBL29834095 | 0.69 | HSD17B10 (0.38) | MEN1KMT2AKDM4E | |
| SCHEMBL17666032 | 0.68 | TDP1 (0.31) | MEN1KMT2ATDP1EYA2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |