Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26774179 | 1.00 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL21887083 | 1.00 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL13993542 | 0.93 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20234855 | 0.88 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL5672367 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL5672385 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL16980514 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CA | |
| SCHEMBL22825652 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CA | |
| SCHEMBL28668694 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CA | |
| SCHEMBL3401880 | 0.87 | GPR119 (0.58) | GPR119PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | GPR119 2500/4885PIK3CD 4429/4885PIK3CA 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.