Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708497 | 1.00 | LIPG (0.45) | LIPGACACBHCRTR1HCRTR2DGAT1 | |
| SCHEMBL26774619 | 1.00 | LIPG (0.45) | LIPGACACBHCRTR1HCRTR2DGAT1 | |
| SCHEMBL26774662 | 0.90 | LIPG (0.41) | LIPGACACBHCRTR1HCRTR2DGAT1 | |
| SCHEMBL28887165 | 0.90 | LIPG (0.61) | LIPGHCRTR1 | |
| SCHEMBL26796992 | 0.90 | LIPG (0.61) | LIPGHCRTR1 | |
| SCHEMBL29935380 | 0.90 | LIPG (0.61) | LIPGHCRTR1 | |
| SCHEMBL23708143 | 0.90 | LIPG (0.61) | LIPGHCRTR1 | |
| SCHEMBL29935465 | 0.90 | LIPG (0.61) | LIPGHCRTR1 | |
| SCHEMBL26774618 | 0.87 | LIPG (0.44) | LIPGACACBHCRTR1HCRTR2DGAT1 | |
| SCHEMBL26774518 | 0.84 | PDE10A (0.46) | LIPGACACBHCRTR1HCRTR2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | LIPG 1423/4885ACACB 3528/4885HCRTR1 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.