Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | POR | P16435 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598593 | 0.74 | TAAR1 (0.44) | AMY1AMAPTRXFP1TAAR1CYP1A2 | |
| SCHEMBL10187272 | 0.73 | TDP1 (0.48) | MAPTCYP1A2SMN1; SMN2TRPA1MEN1 | |
| Methane SCHEMBL27570896 | 0.72 | TAAR1 (0.43) | AMY1AMAPTRXFP1TAAR1CYP1A2 | |
| SCHEMBL1023280 | 0.71 | AMY1A (0.61) | AMY1AMAPTHTTTRPA1MEN1 | |
| SCHEMBL12345571 | 0.71 | AMY1A (0.41) | AMY1AMAPTRXFP1TAAR1CYP1A2 | |
| SCHEMBL7647723 | 0.71 | GABRA1 (0.46) | MAPTL3MBTL1TP53GABRA1GABRB2 | |
| SCHEMBL29462885 | 0.70 | TAAR1 (0.58) | MAPTRXFP1TAAR1CYP1A2HTT | |
| SCHEMBL269825 | 0.70 | TAAR1 (0.58) | MAPTRXFP1TAAR1CYP1A2HTT | |
| SCHEMBL10175432 | 0.70 | GABRA1 (0.38) | CYP1A2SMN1; SMN2TRPA1KDM4EL3MBTL1 | |
| SCHEMBL12509537 | 0.70 | AMY1A (0.39) | AMY1AMAPTRXFP1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365627-A1 | MACROCYCLIC PEPTIDE BORONATE IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365627-A1 | MACROCYCLIC PEPTIDE BORONATE IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | AMY1A 3334/4885MAPT 3153/4885RXFP1 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.