Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676701 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL2677613 | 0.98 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL3828585 | 0.94 | ALDH1A1 (0.78) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL26124277 | 0.92 | HPGD (0.68) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL1309352 | 0.89 | ALDH1A1 (0.86) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL493733 | 0.88 | HPGD (0.61) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL10559542 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL7131881 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL3703105 | 0.87 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNAHPGDHSD11B1 | |
| SCHEMBL27752273 | 0.86 | HPGD (0.72) | ALDH1A1TSHRLMNAHPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173638-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-08 | — | — | US | claimed |
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | US | claimed |
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | claimed |
| US-8173638-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ALDH1A1 1695/4885TSHR 995/4885LMNA 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.