SCHEMBL2678231

SCHEMBL2678231

CCCCCCCCCCCCCCC(C(=O)O)C(C)N

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.53
SPHK1 Q9NYA1 1/20 0.53
FFAR1 O14842 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
MAPT P10636 1/20 0.52
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
TP53 P04637 1/20 0.47
OPRM1 P35372 1/20 0.46
LAP3 P28838 1/20 0.46
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3689951 1.00 GPR84 (0.53) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL6756076 1.00 GPR84 (0.53) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL28696425 1.00 GPR84 (0.53) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL6757020 1.00 GPR84 (0.53) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL7202198 0.92 SLC1A2 (0.50) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL10661368 0.86 CES2 (0.43) GPR84SPHK1FFAR1ACE2GRIK1
SCHEMBL9066915 0.85 GPR84 (0.64) GPR84FFAR1ACE2GRIK1GRIK2
SCHEMBL337767 0.85 GPR84 (0.64) GPR84FFAR1ACE2GRIK1GRIK2
SCHEMBL5547897 0.85 GPR84 (0.64) GPR84FFAR1ACE2GRIK1GRIK2
SCHEMBL337012 0.85 GPR84 (0.64) GPR84FFAR1ACE2GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9107814-B2 Micelle composition of polymer and passenger drug WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-08-18 US disclosed
US-20120309780-A1 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-12-06 US disclosed
US-8173167-B2 Micelle composition of polymer and passenger drug WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-08 US disclosed
WO-2006110862-A9 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RES FOUND (US) 2008-08-07 WO disclosed
EP-1871343-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-01-02 EP disclosed
US-20060251710-A1 Micelle composition of polymer and passenger drug NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-11-09 US disclosed
WO-2006110862-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-10-19 WO disclosed