SCHEMBL2678614

SCHEMBL2678614

Cc1ccc(-c2nc(-c3ccc(OCCCCCC(C)C)cc3)nc(-c3ccc(C)cc3C)n2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.47
GAA P10253 1/20 0.38
ALOX12 P18054 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ACACB O00763 1/20 0.38
ACACA Q13085 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTR1A P08908 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
KCNH2 Q12809 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466959 0.87 RARB (0.41) RARBGAAALOX12NPSR1TDP1
SCHEMBL989628 0.87 RARB (0.41) RARBGAAALOX12NPSR1TDP1
SCHEMBL2678672 0.86 RARB (0.46) RARBACACBACACATP53NPC1
SCHEMBL19265244 0.83 RARB (0.43) RARBACACBACACANPC1RAB9A
SCHEMBL3728973 0.82 RARB (0.39) RARBGAAALOX12NPSR1TP53
SCHEMBL20690907 0.81 PTPN11 (0.38) ACACBACACATP53HTR1B
SCHEMBL2869972 0.79 LMNA (0.42) ACACBACACANPC1RAB9AMEN1
SCHEMBL1424638 0.79 PLA2G4B (0.41) RARBACACBACACATDP1TP53
SCHEMBL4791408 0.79 PLA2G4B (0.41) RARBACACBACACATDP1TP53
SCHEMBL5602705 0.79 PLA2G4B (0.41) RARBACACBACACATDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10100173-B2 Resin additive masterbatch and polyolefin resin composition to which said resin additive masterbatch has been admixed ADEKA CORPORATION (JP) 2018-10-16 US disclosed
EP-2578620-B1 RESIN-ADDITIVE MASTERBATCH ADEKA CORP (JP) 2018-04-25 EP disclosed
EP-2980129-B1 RESIN ADDITIVE MASTERBATCH AND POLYOLEFIN RESIN COMPOSITION TO WHICH SAID RESIN ADDITIVE MASTERBATCH HAS BEEN ADMIXED ADEKA CORP (JP) 2018-03-07 EP disclosed
EP-2949697-B1 RESIN COMPOSITION ADEKA CORP (JP) 2018-01-31 EP disclosed
US-9624355-B2 Resin composition ADEKA CORPORATION (JP) 2017-04-18 US disclosed
US-9574068-B2 Resin additive master batch ADEKA CORPORATION (JP) 2017-02-21 US disclosed
US-20160053086-A1 RESIN ADDITIVE MASTERBATCH AND POLYOLEFIN RESIN COMPOSITION TO WHICH SAID RESIN ADDITIVE MASTERBATCH HAS BEEN ADMIXED ADEKA CORPORATION (JP) 2016-02-25 US disclosed
EP-2980129-A1 RESIN ADDITIVE MASTERBATCH AND POLYOLEFIN RESIN COMPOSITION TO WHICH SAID RESIN ADDITIVE MASTERBATCH HAS BEEN ADMIXED Adeka Corporation (JP) 2016-02-03 EP disclosed
US-9249267-B2 Resin-additive masterbatch ADEKA CORPORATION (JP) 2016-02-02 US disclosed
US-20150353710-A1 RESIN COMPOSITION ADEKA CORPORATION (JP) 2015-12-10 US disclosed
US-20140378586-A1 RESIN ADDITIVE MASTER BATCH ADEKA CORPORATION (JP) 2014-12-25 US disclosed
EP-2810976-A1 RESIN ADDITIVE MASTER BATCH Adeka Corporation (JP) 2014-12-10 EP disclosed
EP-2578620-A1 RESIN-ADDITIVE MASTERBATCH Adeka Corporation (JP) 2013-04-10 EP disclosed
EP-2112200-B1 RESIN ADDITIVE MASTER BATCH ADEKA CORP (JP) 2013-03-27 EP disclosed
US-20130065994-A1 RESIN-ADDITIVE MASTERBATCH ADEKA CORPORATION (JP) 2013-03-14 US disclosed
US-8173735-B2 Resin additive master batch ADEKA CORPORATION (JP) 2012-05-08 US disclosed
US-20100093899-A1 RESIN ADDITIVE MASTER BATCH ADEKA CORPORATION (JP) 2010-04-15 US disclosed
EP-2112200-A1 RESIN ADDITIVE MASTER BATCH Adeka Corporation (JP) 2009-10-28 EP disclosed
US-20090088513-A1 RESIN ADDITIVE COMPOSITION AND RESIN COMPOSITION ADEKA CORPORATION (JP) 2009-04-02 US disclosed
EP-1897914-A1 RESIN ADDITIVE COMPOSITION AND RESIN COMPOSITION Adeka Corporation (JP) 2008-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093899-A1 RESIN ADDITIVE MASTER BATCH PCNA, RAD51, MRE11 RARB 170/4885GAA 1190/4885ALOX12 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.