SCHEMBL2869972

SCHEMBL2869972

Cc1ccc(-c2nc(-c3ccc(OCC(C)O)cc3)nc(-c3ccc(OCC(C)O)cc3)n2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
PDE2A O00408 9/20 0.36
PDE10A Q9Y233 7/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
S1PR1 P21453 1/20 0.36
FFAR1 O14842 1/20 0.35
USP2 O75604 1/20 0.35
TSHR P16473 1/20 0.35
KDM1A O60341 1/20 0.35
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
PSMB5 P28074 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14457411 0.87 NPC1 (0.39) LMNAPDE2APDE10ANPC1KMT2A
SCHEMBL17474752 0.85 ACACB (0.35) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL4791408 0.82 PLA2G4B (0.41) LMNANPC1RAB9AS1PR1USP2
SCHEMBL5602705 0.82 PLA2G4B (0.41) LMNANPC1RAB9AS1PR1USP2
SCHEMBL1424638 0.82 PLA2G4B (0.41) LMNANPC1RAB9AS1PR1USP2
SCHEMBL6472417 0.81 FFAR1 (0.38) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL3426811 0.80 LMNA (0.39) LMNAMEN1KMT2AMAPTS1PR1
SCHEMBL15257157 0.79 PLA2G4B (0.47) NPC1RAB9AUSP2ACACBACACA
SCHEMBL15257156 0.79 PLA2G4B (0.47) NPC1RAB9AUSP2ACACBACACA
SCHEMBL2678614 0.79 RARB (0.47) MEN1NPC1RAB9AKMT2AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230407050-A1 METHOD FOR STABILIZING AN ORGANIC MATERIAL USING A STABILIZER MIXTURE BASF SE (DE) 2023-12-21 US disclosed
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO disclosed
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
EP-3428228-B1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2020-11-25 EP disclosed
EP-3405519-B1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2019-10-16 EP disclosed
EP-3107959-B1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-07-25 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
EP-2828353-B1 ISOINDOLO[2,1-A]QUINAZOLINE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2016-05-18 EP disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
US-5985964-A LUBRICANTS AND FATTY ACID SALTS WITCO VINYL ADDITIVES GMBH (DE) 1999-11-16 US disclosed
US-5767169-A STORAGE STABLE, NONHYDROLYZING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-16 US disclosed
US-5672574-A Stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1997-09-30 US disclosed
EP-0727410-A1 Bisphenol ester derivatives CIBA-GEIGY AG (CH) 1996-08-21 EP disclosed
EP-0723990-A1 Synergistic stabilizing mixture CIBA-GEIGY AG (CH) 1996-07-31 EP disclosed
EP-0365469-B1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
EP-0548015-A1 Tetramethylpiperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1993-06-23 EP disclosed
US-5039799-A Light, heat, oxidation stabilizer CIBA-GEIGY CORPORATION (US) 1991-08-13 US disclosed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed