Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 8/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033286 | 0.95 | MEN1 (0.55) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL16152398 | 0.95 | MEN1 (0.55) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL21168496 | 0.94 | MAOA (0.57) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL607377 | 0.93 | MEN1 (0.51) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL25469335 | 0.90 | MEN1 (0.49) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL16790732 | 0.89 | MEN1 (0.62) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL12244210 | 0.89 | CAPN1 (0.57) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL16152403 | 0.88 | CA1 (0.53) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL18594781 | 0.88 | MEN1 (0.47) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL3200956 | 0.87 | SIRT5 (0.49) | MEN1KMT2AGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023223057-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CYPRALIS LIMITED (GB) | 2023-11-23 | — | — | WO | disclosed |