Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228275 | 0.80 | CHRM2 (0.45) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13631976 | 0.77 | PER2 (0.46) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24796173 | 0.76 | PER2 (0.42) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13621187 | 0.74 | ACE (0.47) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13745122 | 0.74 | KDM4E (0.47) | CHRM2CHRM5CHRM1CHRM3TRPC5 | |
| SCHEMBL23103478 | 0.73 | PER2 (0.40) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25192028 | 0.73 | POLB (0.45) | ALDH1A1 | |
| SCHEMBL14170363 | 0.73 | FPR2 (0.34) | TRPC5ACHEPIK3CD | |
| SCHEMBL13621189 | 0.72 | PER2 (0.42) | PER2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13621190 | 0.72 | PER2 (0.42) | PER2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |