⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26790705 | 0.82 | KDM4E (0.31) | — | |
| SCHEMBL26790716 | 0.77 | SMC2 (0.32) | — | |
| SCHEMBL24463640 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL30391150 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL28995731 | 0.73 | CYP1A2 (0.33) | — | |
| SCHEMBL30390530 | 0.73 | CYP1A2 (0.33) | — | |
| SCHEMBL26790783 | 0.71 | NPC1 (0.31) | — | |
| SCHEMBL26790682 | 0.70 | KDM4E (0.44) | — | |
| SCHEMBL24463148 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL24463421 | 0.69 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374015-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230374015-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. | 2023-11-23 | — | — | US | disclosed |