Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.69 |
| ▸ | BCR | P11274 | 7/20 | 0.66 |
| ▸ | LDLR | P01130 | 3/20 | 0.66 |
| ▸ | KIT | P10721 | 3/20 | 0.66 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.66 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.66 |
| ▸ | HCK | P08631 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | RAF1 | P04049 | 2/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | SRC | P12931 | 2/20 | 0.66 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.66 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.66 |
| ▸ | STK10 | O94804 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679277 | 0.92 | EPHB2 (0.65) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL10078661 | 0.92 | EPHB2 (0.65) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL2679952 | 0.88 | CSF1R (0.62) | ABL1BCRKITSRCLCK | |
| SCHEMBL10077754 | 0.85 | ABL1 (0.50) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL2679720 | 0.85 | ABL1 (0.50) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL10077740 | 0.83 | CSF1R (0.73) | KITEPHB2SRCLCKCSF1R | |
| SCHEMBL2679147 | 0.83 | CSF1R (0.73) | KITEPHB2SRCLCKCSF1R | |
| SCHEMBL14642889 | 0.82 | ABL1 (0.78) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL30546751 | 0.82 | EPHB2 (0.77) | ABL1BCRLDLRKITPCSK9 | |
| SCHEMBL28382296 | 0.82 | EPHB2 (0.77) | ABL1BCRLDLRKITPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426446-B2 | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHARM CO. LTD. (CN) | 2013-04-23 | — | — | US | claimed |
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO. LTD | 2012-05-10 | — | — | US | claimed |
| US-8426446-B2 | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHARM CO. LTD. (CN) | 2013-04-23 | — | — | US | disclosed |
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO. LTD | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | ABL1, ABL2, BCR | ABL1 1/4885BCR 3/4885LDLR 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.