Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26741101 | 0.83 | PGR (0.57) | GAAHPGDMAPTRAB9ATSHR | |
| SCHEMBL26741100 | 0.83 | PGR (0.57) | GAAHPGDMAPTRAB9ATSHR | |
| SCHEMBL20332450 | 0.83 | TSHR (0.70) | GAAKMT2AMEN1HPGDMAPT | |
| SCHEMBL8171158 | 0.82 | GAA (0.57) | GAAKMT2AMEN1HPGDMAPT | |
| SCHEMBL30434985 | 0.82 | GAA (0.53) | GAAKMT2AMEN1HPGDMAPT | |
| SCHEMBL26741094 | 0.82 | SMN1; SMN2 (0.58) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL26741098 | 0.82 | SMN1; SMN2 (0.58) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL10027975 | 0.81 | KDM4E (0.63) | GAAKMT2AMEN1HPGDMAPT | |
| SCHEMBL14643391 | 0.81 | KDM4E (0.63) | GAAKMT2AMEN1HPGDMAPT | |
| SCHEMBL26741265 | 0.80 | TSHR (0.63) | GAAKMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220439-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |