Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171158 | 0.87 | GAA (0.57) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL5093996 | 0.84 | GAA (0.53) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL31362806 | 0.78 | GAA (0.47) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL28382010 | 0.77 | GAA (0.46) | GAAKMT2AMEN1KDM1AHPGD | |
| Hydrochloric Acid SCHEMBL10846536 | 0.77 | LTA4H (0.52) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL29807803 | 0.74 | GAA (0.61) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL3859948 | 0.74 | GAA (0.61) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL17993533 | 0.74 | KDM1A (0.70) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL7723381 | 0.73 | GAA (0.59) | GAAKMT2AMEN1KDM1AHPGD | |
| SCHEMBL9400389 | 0.72 | NPC1 (0.66) | GAAKMT2AMEN1KDM1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948032-A | Furanopyrimidine derivatives | 默克专利股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-117982625-A | Use of TRIM72 in the prevention or treatment of ALS | 神济昌华(北京)生物科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112153978-B | WS-635 and its use in medicine | 中美华世通生物医药科技(武汉)股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-110753557-B | TRIM72 uses ubiquitinated FUS protein mutants as potential therapeutic targets for ALS | 神济昌华(北京)生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-112867715-B | 5-azaindazole derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117222435-A | HER 2-targeted Fc antigen binding fragment-drug conjugates | 默克专利有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-110997662-B | Benzimidazole derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114805139-B | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-111770914-B | Compounds as neurokinin-1 receptor antagonists and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111183142-B | Boric acid derivatives | 默克专利股份公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-110944994-B | Quinoxaline derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2023-06-09 | — | — | CN | disclosed |