Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11967669 | 0.58 | PRKCA (0.30) | — | |
| SCHEMBL2992690 | 0.58 | PRKCA (0.30) | — | |
| SCHEMBL6330248 | 0.52 | MAPT (0.53) | NFKB1NFKB2RELA | |
| SCHEMBL4288449 | 0.50 | POLB (0.33) | NFKB1NFKB2RELA | |
| SCHEMBL9843500 | 0.49 | NFKB1 (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL356851 | 0.48 | — | — | |
| SCHEMBL893130 | 0.48 | — | — | |
| SCHEMBL926102 | 0.48 | — | — | |
| SCHEMBL809499 | 0.48 | MAPT (0.38) | — | |
| SCHEMBL8857064 | 0.48 | CYP19A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012006923-A | USE OF PHTHALIDE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES MELLITUS | DSM IP ASSETS BV | 2012-01-12 | — | — | JP | disclosed |