Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | POLG | P54098 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257625 | 1.00 | LMNA (0.46) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL24229283 | 1.00 | LMNA (0.46) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL15788423 | 0.87 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL27267581 | 0.87 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL24872399 | 0.87 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL12149545 | 0.87 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL15259219 | 0.87 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10511557 | 0.85 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL20117255 | 0.85 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL23808352 | 0.84 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220737-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |