Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecane SCHEMBL28227311 | 1.00 | OPRM1 (0.54) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL8604438 | 1.00 | OPRM1 (0.54) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL9328565 | 1.00 | OPRM1 (0.54) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL21660331 | 1.00 | OPRM1 (0.54) | OPRM1SPHK1CYP2D6TP53LMNA | |
| Dodecane SCHEMBL28226541 | 1.00 | OPRM1 (0.54) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL7554563 | 0.98 | OPRM1 (0.56) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL15167780 | 0.93 | OPRM1 (0.42) | OPRM1SPHK1CYP2D6TP53LMNA | |
| Dodecane SCHEMBL27989001 | 0.91 | OPRM1 (0.48) | OPRM1SPHK1CYP2D6TP53LMNA | |
| Tetradecane SCHEMBL27989285 | 0.91 | OPRM1 (0.48) | OPRM1SPHK1CYP2D6TP53LMNA | |
| SCHEMBL2416094 | 0.90 | OPRM1 (0.46) | OPRM1SPHK1CYP2D6TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365531-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365531-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS | METAP1, SARS1, RTF1 | OPRM1 2914/4885SPHK1 962/4885CYP2D6 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.