Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911031 | 0.88 | GAA (0.56) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL17552253 | 0.88 | GAA (0.56) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL28561573 | 0.85 | POLB (0.64) | ALDH1A1TSHRMAPTTP53GAA | |
| SCHEMBL21313822 | 0.78 | MAPT (0.59) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL26798520 | 0.78 | MAPT (0.64) | ALDH1A1TSHRHSD17B10MAPTTP53 | |
| SCHEMBL29911200 | 0.78 | MAPT (0.58) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL19422864 | 0.78 | MAPT (0.58) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL17552174 | 0.76 | MAPT (0.57) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL17540892 | 0.76 | TP53 (0.58) | ALDH1A1TSHRHSD17B10MAPTTHRB | |
| SCHEMBL29831415 | 0.76 | MAPT (0.57) | ALDH1A1TSHRHSD17B10MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827626-B2 | Quinolines that modulate SERCA and their use for treating disease | NEURODON CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827626-B2 | Quinolines that modulate SERCA and their use for treating disease | ATP2A1, ATP2A3, ATP2A2 | ALDH1A1 1661/4885TSHR 3549/4885HSD17B10 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.