Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 4/20 | 0.71 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.61 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.60 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.60 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.60 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.60 |
| ▸ | NNMT | P40261 | 3/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.60 |
| ▸ | TRDMT1 | O14717 | 3/20 | 0.60 |
| ▸ | WDR5 | P61964 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RBBP5 | Q15291 | 2/20 | 0.60 |
| ▸ | DPY30 | Q9C005 | 2/20 | 0.60 |
| ▸ | ASH2L | Q9UBL3 | 2/20 | 0.60 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.60 |
| ▸ | INMT | O95050 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 2/20 | 0.60 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.60 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086452 | 0.91 | MARS1 (0.72) | MARS1EZH2DOT1LSMYD3SETD2 | |
| SCHEMBL19100209 | 0.91 | MARS1 (0.72) | MARS1EZH2DOT1LSMYD3SETD2 | |
| SCHEMBL38665162 | 0.85 | MARS1 (0.65) | MARS1EZH2DOT1LSMYD3SETD2 | |
| SCHEMBL4727574 | 0.82 | MARS1 (0.61) | MARS1EZH2DOT1LSMYD3SETD2 | |
| SCHEMBL30819188 | 0.82 | MARS1 (0.61) | MARS1EZH2DOT1LSMYD3SETD2 | |
| Adenosine SCHEMBL3014297 | 0.82 | MARS1 (0.77) | MARS1EZH2DOT1LSETD2CARM1 | |
| Adenosine SCHEMBL27500408 | 0.82 | MARS1 (0.77) | MARS1EZH2DOT1LSETD2CARM1 | |
| Adenosine SCHEMBL3014288 | 0.82 | MARS1 (0.77) | MARS1EZH2DOT1LSETD2CARM1 | |
| SCHEMBL21053165 | 0.81 | MARS1 (0.68) | MARS1EZH2DOT1LSETD2CARM1 | |
| SCHEMBL215732 | 0.81 | MARS1 (0.68) | MARS1EZH2DOT1LSETD2CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889392-B2 | Monolignol 4-O-methyltransferases and uses thereof | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120117694-A1 | Novel Monolignol 4-O-Methyltransferases and Uses Thereof | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2012-05-10 | — | — | US | disclosed |