Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 4/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.60 |
| ▸ | AHCY | P23526 | 1/20 | 0.58 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.54 |
| ▸ | GNMT | Q14749 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RBBP5 | Q15291 | 3/20 | 0.54 |
| ▸ | DPY30 | Q9C005 | 3/20 | 0.54 |
| ▸ | ASH2L | Q9UBL3 | 3/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.52 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.52 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.52 |
| ▸ | NNMT | P40261 | 2/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.52 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.52 |
| ▸ | INMT | O95050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184990 | 0.91 | AHCY (0.62) | DOT1LAHCYEZH2GNMTWDR5 | |
| SCHEMBL5086452 | 0.83 | MARS1 (0.72) | MARS1DOT1LAHCYEZH2WDR5 | |
| SCHEMBL19100209 | 0.83 | MARS1 (0.72) | MARS1DOT1LAHCYEZH2WDR5 | |
| SCHEMBL2679879 | 0.82 | MARS1 (0.71) | MARS1DOT1LAHCYEZH2WDR5 | |
| SCHEMBL19111341 | 0.80 | SMYD3 (0.66) | DOT1LEZH2WDR5KMT2ARBBP5 | |
| SCHEMBL14905991 | 0.78 | CARM1 (0.59) | DOT1LAHCYSETD2TRDMT1NNMT | |
| SCHEMBL38665162 | 0.78 | MARS1 (0.65) | MARS1DOT1LEZH2WDR5KMT2A | |
| SCHEMBL622588 | 0.76 | ADORA1 (0.69) | DOT1LAHCYKMT2AADORA1 | |
| SCHEMBL3014292 | 0.76 | MARS1 (1.00) | MARS1DOT1LEZH2WDR5KMT2A | |
| SCHEMBL583457 | 0.76 | MARS1 (1.00) | MARS1DOT1LEZH2WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| EP-1812454-A2 | CHEMICAL SYNTHESIS OF S-ADENOSYL-L-METHIONINE WITH ENRICHMENT OF (S,S)-ISOMER | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006000883-A2 | CHEMICAL SYNTHESIS OF S-ADENOSYL-L-METHIONINE WITH ENRICHMENT OF (S,S)-ISOMER | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2006-01-05 | — | — | WO | disclosed |