Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 10/20 | 0.63 |
| ▸ | RECQL | P46063 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MTOR | P42345 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053003 | 0.81 | PLA2G1B (0.55) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL26798590 | 0.79 | ALOX15 (0.71) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL19342843 | 0.79 | ALOX15 (0.71) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL2562361 | 0.79 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL9905877 | 0.79 | TAAR1 (0.61) | BLMESR1SLC6A2OPRK1SLC7A5 | |
| SCHEMBL13660697 | 0.79 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL29379558 | 0.79 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL633687 | 0.79 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL17244102 | 0.78 | PLA2G1B (0.65) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| Masoprocol SCHEMBL3818 | 0.78 | ALOX15 (1.00) | ALOX15RECQLKDM4ETDP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348506-A1 | MACROCYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348506-A1 | MACROCYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF | VNN1, VKORC1, VKORC1L1 | ALOX15 2064/4885RECQL 216/4885KDM4E 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.