Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803026 | 0.99 | CA1 (0.40) | SIRT6SIRT1CA1MMP3PLA2G2C | |
| SCHEMBL26803199 | 0.94 | CA1 (0.41) | SIRT6SIRT1CA1MMP3CNR1 | |
| SCHEMBL26804556 | 0.94 | CA1 (0.41) | SIRT6SIRT1CA1MMP3CNR1 | |
| SCHEMBL26803193 | 0.92 | SIRT6 (0.38) | SIRT6SIRT1CA1MMP3PLA2G2C | |
| SCHEMBL26804020 | 0.91 | SIRT6 (0.46) | SIRT6SIRT1CA1CNR1PLA2G10 | |
| SCHEMBL26805124 | 0.90 | SIRT6 (0.48) | SIRT6SIRT1CNR1 | |
| SCHEMBL26803036 | 0.89 | PLA2G10 (0.36) | SIRT6SIRT1CA1MMP3PLA2G2C | |
| SCHEMBL26804341 | 0.89 | PLA2G10 (0.36) | SIRT6SIRT1CA1MMP3PLA2G2C | |
| SCHEMBL26803848 | 0.88 | SIRT6 (0.46) | SIRT6SIRT1CNR1 | |
| SCHEMBL26804026 | 0.86 | NOD1 (0.40) | SIRT6SIRT1PLA2G2CBIRC2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225650-A1 | LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES | OLIX US, INC. (US) | 2023-11-23 | — | — | WO | disclosed |