Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20086105 | 0.83 | MAPT (0.37) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL15344994 | 0.74 | CYP1A2 (0.42) | KDM4EMAPTALDH1A1NSD2KCNH2 | |
| SCHEMBL15943822 | 0.73 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1NSD2KCNH2 | |
| SCHEMBL24457554 | 0.72 | KDM4E (0.48) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL22445824 | 0.72 | KDM4E (0.40) | KDM4EMAPTALDH1A1NSD2KMT2A | |
| SCHEMBL24165627 | 0.72 | KDM4E (0.40) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL19836258 | 0.69 | KDM4E (0.38) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL26662601 | 0.69 | KDM4E (0.38) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL15341871 | 0.69 | KDM4E (0.38) | KDM4EMAPTALDH1A1NSD2 | |
| SCHEMBL23554308 | 0.68 | CCR1 (0.41) | KDM4EMAPTALDH1A1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | KDM4E 1788/4885MAPT 4565/4885ALDH1A1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.